Acute response and chronic stimulus for cardiac structural and functional adaptation in a professional boxer.


The individual response to acute and chronic changes in cardiac structure and function to intense exercise training is not fully understood and therefore evidence in this setting may help to improve the timing and interpretation of pre-participation cardiac screening. The following case report highlights an acute increase in right ventricular (RV) size and a reduction in left ventricular (LV) basal radial function with concomitant increase at the mid-level in response to a week’s increase in training volume in a professional boxer. These adaptations settle by the second week; however, chronic physiological adaptation occurs over a 12-week period. Electrocardiographic findings demonstrate an acute lateral T-wave inversion at 1 week, which revert to baseline for the duration of training. It appears that a change in training intensity and volume generates an acute response within the RV that acts as a stimulus for chronic adaptation in this professional boxer.

Oxf Med Case Reports. 2014 Jun 27;2014(3):65-8. doi: 10.1093/omcr/omu026. eCollection 2014.
Oxborough D1, George K1, Utomi V1, Lord R1, Morton J1, Jones N2, Somauroo J3.

Author information

  • 1Research Institute for Sports and Exercise Sciences , Liverpool John Moores University , Liverpool L3 3FT , UK.
  • 2Orthopaedic , Aintree University Hospitals NHS Trust and British Boxing Board of Control , London , UK.
  • 3Research Institute for Sports and Exercise Sciences , Liverpool John Moores University , Liverpool L3 3FT , UK ; Cardio-Respiratory and Vascular Department , Countess of Chester Hospital NHS Trust , Chester , UK.

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